Valle San Giovanni can be found within the province of Teramo, in the Abruzzo region of central Italy. It is a frazione of the communal capital of Teramo sitting. The village has a population of about 350 people and lies about six miles from Teramo. The Adriatic Sea and the Gran Sasso are about 25 km away. It sits in the Tordino Valley, near the spot where two small streams, the Lete and the Fiumicello, flow into the Tordino river.