Cardiovascular quiz
“What are the novel findings in the manuscript “Angiotensin II- and Salt-Induced Kidney Injury”?” Novel finding was that in highly producing Ang II Tsukuba hypertensive mice (THM), which is a model of enhanced renin–angiotensin–aldosterone system (RAAS), the Ang II/salt can enhance injury of the kidney through Rac1-stimulated mineralocorticoid receptor (MR) rather than Ang II receptor-stimulated pathway.
“What is the effect of low and high salt on blood pressure and kidney function in normal mice (C57)?”Low-salt intake as well as high-salt intake has no effect on the systolic blood pressure of the normal mice (C57). On the other hand, kidney function can be determined by the urinary albumin excretion that is usually kept low by Continue reading...