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Largely, during organogenesis in utero and briefly during adult life, bone marrow is responsible for the supply of lymphocyte precursors. The cell population in the thymus is transformed into T-Lymphocytes under the effect of environmental factors. While unlike birds, mammals are devoid of bursa and B Lymphocytes transformation is exclusive to liver in utero and bone marrow after birth. These processed T and B Lymphocytes then migrate to the lymph nodes from their respective originating tissues. Morphologically it is impossible to differentiate T Continue reading...
