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Figure 1: Down regulation of XIAP by specific inhibitor Embelin inhibits cell viability in a dose dependent manner. Investigation was conducted to determine the role of XIAP in the pathogenesis of BC and the impact of its down regulation in the inhibition of BC cell viability. Fig. 1 showed that all cell lines (CAL120, EVSAT, MCF7, and MDAMB231) experienced enormous drop to <40% in mean cell viability at 50μm, with least outcome variability found in EVSAT cell line, indicating dose-dependent vulnerability to Embelin action. Although the MCF7 cell line averaged < Continue reading...