Mood Disorders Research Papers Example

Mood disorders are some of the most common neuropsychiatric medical conditions that are under serious study. There are many causes for mood disorders including genetics, chronic stress, or medical illness, isolation, poor coping mechanisms to stress, and abnormal functioning of the brain. This paper focuses on the abnormal functioning of the brain with a close look on the affected part of the brain in the pathophysiology of mood disorders.
Wayne C. Drevets, Joseph L. Price, and Maura L. Furey (2008) investigated the structural and functional abnormalities in mood disorders. They noted that the medial prefrontal network, the hippocampus, ventromedial parts of the basal ganglia, were associated with depression when the gray matter volume is altered. These sections of the brain would thus lead to mood disorders if affected. Dos Ongur, Wayne C. Drevests, and Joseph L. Price (1998) investigated the roles of the glial reduction in the subgenual prefrontal cortex in mood disorders with unbiased stereological techniques. The results indicated that glial reduction may have effects on the pathogenesis of depression but only in combination with other factors that affects the neural activity such, as serotonin, dopamine, and noradrenaline.
Robert g. Robinson , Kenneth l. Kubos , Lyn book star , Krishna Rao , Thomas r. price (1884) investigated the importance on the location of lesion that affects mood disorders in stroke patients. They found that the depression level was significantly increased when the lesion is located in the left anterior as opposed to any other location of the lesion. Anabel Martínez-Arán, Eduard Vieta, María Reinares, Francesc Colom, Carla Torrent, Jose Sánchez-Moreno, Antonio Benabarre, José Manuel Goikolea, Mercè Comes, and Manel Salamero (2004) found that patients with depression, bipolar disorder, and the maniacs show dysfunction in the frontal and verbal memory. In conclusion, it is evident that there are various parts of the brain that lead to different mood disorders with different severity.

References

Drevets C. W, Price J. L., and Furey M. L. (2008). Brain Structural and functional abnormalities in mood disorders: implications for neurocircuitry models of depression. PDF. Retrieved on February 27, 2015 from <http://link.springer.com/article/10.1007/s00429-008-0189-x>
Ongur D. Drevets C. W, and Price J. L (1998). Glial reduction in the subgenual prefrontal cortex in mood disorders. Retrieved on February 27, 2015 from <http://www.pnas.org/content/95/22/13290.full>
Robinson G. R., Kubos K. L., Star B. K., Rao K., Price R. T (1884). MOOD DISORDERS IN STROKE PATIENTS: IMPORTANCE OF LOCATION OF LESION. Abstract. Retrieved on February 27, 2015 from < http://brain.oxfordjournals.org/content/107/1/81.short>
Martínez-Arán Anabel , Vieta Eduard , Reinares María , Colom Francesc , Torrent Carla , Sánchez-Moreno Jose , Benabarre Antonio , Goikolea José Manuel , Comes Mercè , Salamero Manel (2004). Cognitive Function Across Manic or Hypomanic, Depressed, and Euthymic States in Bipolar Disorder. Retrieved on February 27, 2015 from <http://ajp.psychiatryonline.org/doi/full/10.1176/appi.ajp.161.2.262>